Thursday, April 3, 2014

Absent stratum granulosum

Absent Stratum Granulosum

This is seen in ichthyosis vulgaris and under a porokeratotic cornoid lamella.

View a Virtual Slide of Ichthyosis vulgaris

View a Virtual slide of DSAP

There is also hypogranulosis seen in any disorder with marked parakeratosis particularly psoriasis. It is also seen in Necrolytic migratory erythema, Acrodermatitis enteropathica and Pellagra. It is also a feature of normal mucous membranes.



Cornoid lamellae usually point inwards towards a porokeratosis. When they are vertical and multiple consider porokeratosis ptychotropica (Verrucous porokeratosis of the gluteal cleft) if multiple dark papules on the buttock of long duration.

View this reference

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